Tolvaptan is an ADH antagonist. We will have few indications, but in the rare true SIADH patient, this drug will have some value. I do not know the cost.
I see many hyponatremia patients, and few of them have persistent SIADH. I am glad to have this option for those rare patients.
The NEJM had a couple of important articles about tolvaptan a couple of years ago.